Glucocorticoids should be used with caution in patients with which condition?

Glucocorticoids should be used with caution in patients with which condition?

• A. Pneumonia
• B. Hepatic disease
• C. Hypotension
• D. Diabetes mellitus

Answer: (D)

Glucocorticoids should be used with caution in patients with diabetes mellitus due to their impact on glucose metabolism. These agents can cause hyperglycemia by causing insulin resistance and increasing gluconeogenesis and glycogenolysis in the liver. This is particularly concerning for patients with diabetes, as it can lead to exacerbation of their condition, making it more difficult to control blood sugar levels. Therefore, careful monitoring and dose adjustments may be necessary when prescribing glucocorticoids to patients with diabetes. In regard to the other conditions listed, while there may be considerations for their management with glucocorticoids, they do not present the same level of immediate concern regarding the metabolic effects seen in diabetic patients.

Glucocorticoids should be used with caution in patients with diabetes mellitus due to their impact on glucose metabolism. These agents can cause hyperglycemia by causing insulin resistance and increasing gluconeogenesis and glycogenolysis in the liver. This is particularly concerning for patients with diabetes, as it can lead to exacerbation of their condition, making it more difficult to control blood sugar levels. Therefore, careful monitoring and dose adjustments may be necessary when prescribing glucocorticoids to patients with diabetes.

In regard to the other conditions listed, while there may be considerations for their management with glucocorticoids, they do not present the same level of immediate concern regarding the metabolic effects seen in diabetic patients.